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Refined characterization of circulating tumor DNA through biological feature integration

Abstract Circulating tumor DNA (ctDNA) in blood plasma is present at very low concentrations compared to cell-free DNA (cfDNA) of non-tumor origin. To enhance ctDNA detection, recent studies have been focused on understanding the non-random fragmentation pattern of cfDNA. These studies have investig...

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Bibliografische gegevens
Hoofdauteurs: Havell Markus, Dineika Chandrananda, Elizabeth Moore, Florent Mouliere, James Morris, James D. Brenton, Christopher G. Smith, Nitzan Rosenfeld
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2022-02-01
Reeks:Scientific Reports
Online toegang:https://doi.org/10.1038/s41598-022-05606-z
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