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Intragraft donor-specific antibodies reflect histologic heterogeneity in kidney allografts with concurrent serum DSA

BackgroundCirculating donor-specific antibodies (sDSA) are clinically important markers of alloimmune risk, but their presence or strength does not always correspond to concurrent antibody-mediated rejection (ABMR) in kidney transplantation. We investigated whether intragraft donor-specific antibodi...

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Principais autores: Hyunjae Lee, Eun Youn Roh, Tae-Shin Kim, Yu Jung Choi, Inseong Oh, Hajeong Lee, Sang Il Min, Chang Wook Jeong, Hee Gyung Kang, Jongwon Ha, Kyung Chul Moon, Eun Young Song
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:Frontiers in Immunology
Fag:
antibody-mediated rejection
Banff classification
biopsy eluate
HLA antibodies
intragraft donor-specific antibodies
kidney transplantation
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1878975/full
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