Prioritization of genetic variants predisposing to coronary heart disease in the Bulgarian population using centenarian exomes

Coronary heart disease (CHD) is a major cause of mortality and morbidity in Europe. CHD is usually caused by atherosclerosis. Despite extensive studies that have identified a large number of genetic variants, strong evidence of association with CHD are not easily replicable in different populations....

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Autori principali:	Mihail Ganev, Lubomir Balabanski, Dimitar Serbezov, Sena Karachanak-Yankova, Radoslava Vazharova, Desislava Nesheva, Zora Hammoudeh, Dragomira Nikolova, Olga Antonova, Rada Staneva, Marta Mihaylova, Vera Damyanova, Savina Hadjidekova, Draga Toncheva
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2019-01-01
Serie:	Biotechnology & Biotechnological Equipment
Soggetti:	coronary heart disease associated variants whole-exome sequencing centenarians bulgarian
Accesso online:	http://dx.doi.org/10.1080/13102818.2019.1700164
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