Protective effect of lycorine hydrochloride against diabetic nephropathy in high-fat diet and streptozotocin-induced diabetic mice

Diabetic nephropathy (DN) poses a significant risk to individuals with diabetes. Inflammation plays a crucial role in DN pathogenesis. Lycorine hydrochloride (LH) is derived from Lycoris radiata (L'Hér.). This herb has been identified as a potent anti-inflammatory molecule. Further studies indicated...

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Auteurs principaux:	Kai-Li Fang, Xin-Yu Qi, Qing-Tong Han, Lu-Zhou Chen, Xiao-Ning Wang, Zhen-Peng Xu, Lu-Qing Shang, Tao Shen
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-12-01
Collection:	Pharmaceutical Science Advances
Sujets:	Diabetic nephropathy Lycorine hydrochloride NF-κB NLRP3 inflammasome
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2773216924000011
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