Novel transcriptional regulation of the GAP promoter in Pichia pastoris towards high expression of heterologous proteins

Abstract Background Pichia pastoris (Komagataella phaffii) is a promising production host, but the usage of methanol limits its application in the medicine and food industries. Results To improve the constitutive expression of heterologous proteins in P. pastoris, four new potential transcription re...

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Autori principali:	Xiangna Lin, Weiqiu Ding, Shaoyan Zheng, Lianna Wu, Xue Chen, Chunfang Xie, Daling Liu, Dongsheng Yao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-07-01
Serie:	Microbial Cell Factories
Soggetti:	Constitutive expression pGAP P. pastoris Transcription factor Heterologous protein
Accesso online:	https://doi.org/10.1186/s12934-024-02435-9
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