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CpG Oligodeoxynucleotides Modulate Innate and Adaptive Functions of IgM+ B Cells in Rainbow Trout

Oligodeoxynucleotides (ODN) containing unmethylated CpG motifs have been widely postulated as vaccine adjuvants both in mammals and teleost fish. However, to date, the effects that CpGs provoke on cells of the adaptive immune system remain mostly unexplored in fish. Given that rainbow trout (Oncorhy...

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Autori principali: Rocío Simón, Patricia Díaz-Rosales, Esther Morel, Diana Martín, Aitor G. Granja, Carolina Tafalla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-03-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/article/10.3389/fimmu.2019.00584/full
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