Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis

Abstract Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have been implicated in the development of T-cell acute lymphoblastic leukemia (T-ALL). To better understand changes in the bone marrow mi...

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Detalhes bibliográficos

Principais autores:	Swati S. Bhasin, Beena E. Thomas, Ryan J. Summers, Debasree Sarkar, Hope Mumme, William Pilcher, Mohamed Emam, Sunil S. Raikar, Sunita I. Park, Sharon M. Castellino, Douglas K. Graham, Manoj K. Bhasin, Deborah DeRyckere
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2023-08-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-023-39152-z
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