Label-free detection of conformational changes in switchable DNA nanostructures with microwave microfluidics

Methods to study conformational changes in biomolecules are limited in resolution and require labelling or other modifications of target analytes. Here the authors present a label-free, microwave microfluidic approach to detect conformational changes of DNA nanostructures based on ionic conductivity...

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Autores principales:	Angela C. Stelson, Minghui Liu, Charles A. E. Little, Christian J. Long, Nathan D. Orloff, Nicholas Stephanopoulos, James C. Booth
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2019-03-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-019-09017-z
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