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LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer

Abstract Background Colorectal liver metastases (CRLM) continue to have a low survival rate. The number of CRLM regulators and clinical indicators remains limited. Long non-coding RNAs (lncRNAs) are a new master regulator of cell invasion and metastasis. However, the function and regulation mechanis...

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Principais autores: Zhe Wang, Jianfang Chen, Fengjun Sun, Xiang Zhao, Yan Dong, Songtao Yu, Jianjun Li, Houjie Liang
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2022-07-01
סדרה:Cell & Bioscience
נושאים:
Colorectal cancer
lncRNA CRLM1
hnRNPK
Metastasis
Gene expression
גישה מקוונת:https://doi.org/10.1186/s13578-022-00849-9
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