Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

Abstract Background Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastasis. Polysialylation of NCAM is mediated by two Golgi-resident polysialy...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Stefan Somplatzki, Martina Mühlenhoff, Andrea Kröger, Rita Gerardy-Schahn, Thomas Böldicke
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2017-05-01
سلاسل:	BMC Biotechnology
الموضوعات:	Neural cell adhesion molecule Polysialyltransferases ER intrabodies Polysialic acid cell surface expression Xenograft tumor mouse model
الوصول للمادة أونلاين:	http://link.springer.com/article/10.1186/s12896-017-0360-7
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!