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Phage Lambda P Protein: Trans-Activation, Inhibition Phenotypes and their Suppression

The initiation of bacteriophage λ replication depends upon interactions between the oriλ DNA site, phage proteins O and P, and E. coli host replication proteins. P exhibits a high affinity for DnaB, the major replicative helicase for unwinding double stranded DNA. The concept of P-lethality relates...

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Principais autores: Connie Hayes, Wen Wang, Kristen Marciniuk, Sidney Hayes, Monique A. Horbay, Craig Erker
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2013-02-01
coleção:Viruses
Assuntos:
E. coli DnaB replicative helicase
bacteriophage lambda (λ) replication initiation protein P
allelic alterations of dnaB and P
ColE1 plasmid curing and replication inhibition
cellular filamentation
Acesso em linha:http://www.mdpi.com/1999-4915/5/2/619
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