Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances

Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated the inhibitory potential of selected naturally occurring phenolic substances on Leishmania infantum arginase (ARGLi) and investigated their an...

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Detalhes bibliográficos

Principais autores:	Andreza R. Garcia, Danielle M. P. Oliveira, Ana Claudia F. Amaral, Jéssica B. Jesus, Ana Carolina Rennó Sodero, Alessandra M. T. Souza, Claudiu T. Supuran, Alane B. Vermelho, Igor A. Rodrigues, Anderson S. Pinheiro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-01-01
coleção:	Journal of Enzyme Inhibition and Medicinal Chemistry
Assuntos:	leishmania infantum visceral leishmaniasis arginase inhibitor rosmarinic acid caffeic acid
Acesso em linha:	http://dx.doi.org/10.1080/14756366.2019.1616182
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