Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice

ABCA1 plays a key role in the initial lipidation of apoA-I, which generates circulating HDL cholesterol. Whereas it is known that the transcriptional upregulation of ABCA1 promotes HDL formation and reverse cholesterol transport (RCT), it is not known how the inhibition of ABCA1 protein degradation...

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Bibliografische gegevens

Hoofdauteurs:	LinZhang Huang, BaoYan Fan, Ang Ma, Philip W. Shaul, HaiBo Zhu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2015-05-01
Reeks:	Journal of Lipid Research
Onderwerpen:	ATP binding cassette transporter A1 high density lipoprotein macrophage reverse cholesterol transport
Online toegang:	http://www.sciencedirect.com/science/article/pii/S0022227520312384
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