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Biological characterization of multidrug-resistant Pseudomonas aeruginosa phage PaeP_Ls and its efficacy in septic mice

ABSTRACT With the widespread use of antibiotics, multidrug-resistant Pseudomonas aeruginosa (MRPA) is increasing year by year. Phage therapy is gaining more and more attention as an alternative therapy to antibiotics. The main objective of this study was to assess the efficacy of PaeP_Ls phage again...

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Main Authors: Shuhong Luo, Li He, Ling Wu, Yong Zhang, Lin Ning, Juan Chen, Jian Hu, Jiajiao Liu, Qin Wang, Yujie Bai, Jian Feng, Fuxiang Li
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2026-02-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
phage
genetic analysis
phage-resistant bacterial variant
sepsis
phage therapy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02050-25
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