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A triad of gut dysbiosis, dysregulated immunity, and ‘leaky’ gut characterize HCMV associated neonatal cholestasis

Abstract Background Gut microbiome dysbiosis and related immune dysfunction have been associated with the pathogenesis of Human Cytomegalovirus (HCMV) infection in infants with neonatal cholestasis (NC) as previously reported by us. However, the interaction of a perturbed microbiome, HCMV infection,...

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Autori principali: Kalyani Karandikar, Gauri Bhonde, Harsha Palav, Varsha Padwal, Shilpa Velhal, Jacintha Pereira, Himali Meshram, Akshat Goel, Ira Shah, Vainav Patel, Vikrant M. Bhor
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-11-01
Serie:Gut Pathogens
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Accesso online:https://doi.org/10.1186/s13099-024-00663-3
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