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Botulinum neurotoxin: from molecular pathogenesis to emerging countermeasures

Abstract Botulism is a severe neuroparalytic syndrome caused by botulinum neurotoxins (BoNTs)—among the most potent biological agents—with an estimated human lethal dose (LD50) of approximately 1 ng/kg. By cleaving soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) protein...

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Bibliographic Details
Main Author: Sultan Almudimeegh
Format: Artigo
Language:Inglês
Published: Springer 2026-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:https://doi.org/10.1007/s44446-026-00090-2
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