Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

Articular cartilage defects remain an intractable clinical challenge due to the limited capacity of cartilage for self‐renewal and repair. Excessive accumulation of reactive oxygen species (ROS) leads to mitochondrial dysfunction, inflammation, and chondrocyte senescence, impeding cartilage regenera...

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Detalhes bibliográficos

Principais autores:	Shu‐Hang He, Zhi‐Han Shen, Ren Zhang, Po‐Lin Liu, Xu‐Ran Li, Qing‐Song Deng, Yu‐Chen Zhang, Ang Wang, Xiao‐Qiu Dou, Shang‐Chun Guo, Shi‐Cong Tao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley-VCH 2025-07-01
coleção:	Small Structures
Assuntos:	cartilage regeneration nanozyme‐reinforced hydrogel reactive oxygen species scavenging senescent microenvironment stimulator of interferon genes inhibition
Acesso em linha:	https://doi.org/10.1002/sstr.202400592
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