Mesenchymal stem cell-derived exosomes can alleviate GVHD and preserve the GVL effect in allogeneic stem cell transplantation animal models

BackgroundMesenchymal stem cells (MSCs) can alleviate graft-versus-host disease (GVHD) in hematopoietic stem cell transplantation (HSCT). MSCs-derived exosomes (MEXs) can mirror the biological function of their parent cells. Whether MEXs can alleviate GVHD like their parent cells or not is unclear....

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Detalhes bibliográficos

Principais autores:	Yan Jiang, Jie Zhao, Minghui Wang, Fang Huang, Jiaqi Li, Rui Liu, Jiangbo Wan, Siguo Hao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-12-01
Colecção:	Frontiers in Immunology
Assuntos:	mesenchymal stem cells exosomes hematopoietic stem cell transplantation graft-versus-host disease graft-versus-leukemia
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1284936/full
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