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Correcting Differential Gene Expression Analysis for Cyto—Architectural Alterations in Substantia Nigra of Parkinson’s Disease Patients Reveals Known and Potential Novel Disease—Associated Genes and Pathways

Several studies have analyzed gene expression profiles in the substantia nigra to better understand the pathological mechanisms causing Parkinson’s disease (PD). However, the concordance between the identified gene signatures in these individual studies was generally low. This might have been caused...

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Huvudupphov: Federico Ferraro, Christina Fevga, Vincenzo Bonifati, Wim Mandemakers, Ahmed Mahfouz, Marcel Reinders
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2022-01-01
Serie:Cells
Ämnen:
Parkinson’s disease
transcriptome analysis
cyto-architecture
meta-analysis
interactome analysis
Länkar:https://www.mdpi.com/2073-4409/11/2/198
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