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4,4′-DMAR in-vivo acute cardiotoxicity: differences between (±)cis-4,4′-DMAR and its coadministration with the (±)trans-4,4′-DMAR isomer

Backgrounds/aimsSynthetic stimulants represent the largest group of new psychoactive substances and include the aminorex class, which possess anorectic properties and a pharmacological profile similar to that of amphetamine. Among these, 4,4′-dimethylaminorex (4,4′-DMAR) is one of the best-known syn...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Giorgia Corli, Elisa Roda, Beatrice Marchetti, Micaela Tirri, Sabrine Bilel, Marta Bassi, Beatrice Benedetti, Elena Cavarretta, Giacomo Frati, Fabrizio De Luca, Carlo Alessandro Locatelli, Fabio De-Giorgio, Matteo Marti
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-06-01
Schriftenreihe:Frontiers in Cardiovascular Medicine
Schlagworte:
4,4′-DMAR
arrhythmia
cardiotoxicity
NPS
stimulant
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1763456/full
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