Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model
Deposition, remodeling, and signaling of the extracellular matrix facilitate tumor growth and metastasis. Here, we demonstrated that an enzyme, collagen prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), which is involved in collagen synthesis and deposition, had elevated expression in colorectal ca...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020-04-01
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| coleção: | Translational Oncology |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1936523320301030 |
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