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Regulatory Roles of E3 Ubiquitin Ligases and Deubiquitinases in Bone

E3 ubiquitin ligases and deubiquitinating enzymes (DUBs) are pivotal regulators of bone homeostasis, orchestrating osteoblast differentiation, proliferation, and osteoclast activity by controlling protein degradation and stability. This review delineates the roles of key E3 ligases (e.g., Smurf1, Sm...

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Principais autores: Haotian He, Lifei Wang, Bao Xian, Yayi Xia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-05-01
Serier:Biomolecules
Fag:
bone homeostasis
E3 ubiquitin ligases
DUBs
osteoblast differentiation
ubiquitination
Online adgang:https://www.mdpi.com/2218-273X/15/5/679
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