Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

Background: Genetic immunization is expected to induce the expression of antigens in a native form. The encoded peptide epitopes are presented on endogenous MHC molecules, mimicking antigen presentation during a viral infection. We have explored the potential of enfuvirtide (T20), a short HIV peptid...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	S. Stenler, K. E. Lundin, L. Hansen, S. Petkov, N. Mozafari, M. Isaguliants, P. Blomberg, C. I. E. Smith, D. M. Goldenberg, C.-H. Chang, K. Ljungberg, J. Hinkula, B. Wahren
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2017-12-01
Schriftenreihe:	Human Vaccines & Immunotherapeutics
Schlagworte:	genetic vectors minicircle replicon vector dna-immunology hiv-1 membrane proximal enfuvirtide
Online-Zugang:	http://dx.doi.org/10.1080/21645515.2017.1338546
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