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Tolerability of intensified intravenous interferon alfa-2b versus the ECOG 1684 schedule as adjuvant therapy for stage III melanoma: a randomized phase III Italian Melanoma Inter-group trial (IMI – Mel.A.) [ISRCTN75125874]

<p>Abstract</p> <p>Background</p> <p>High-dose interferon alfa-2b (IFNalfa-2b), according to the ECOG 1684 schedule, is the only approved adjuvant treatment for stage III melanoma patients by the FDA and EMEA. However, the risk/benefit profile has been questioned limiting its world-wide use. In the...

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Autores principales: Ridolfi Ruggero, Naglieri Emanuele, Dalla Palma Maurizio, Paccagnella Adriano, Guida Michele, Romanini Antonella, Del Bianco Paola, Chiarion-Sileni Vanna, Silvestri Barbara, Michiara Maria, De Salvo Gian Luca
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2006-02-01
Colección:BMC Cancer
Acceso en línea:http://www.biomedcentral.com/1471-2407/6/44
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