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Evaluation of pediatric epigenetic clocks across multiple tissues

Abstract Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination. Results Our study used data from seven tissue types on three DNA methylation profiling microarrays and f...

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Kaydedildi:
Asıl Yazarlar: Fang Fang, Linran Zhou, Wei Perng, Carmen J. Marsit, Anna K. Knight, Andres Cardenas, Max T. Aung, Marie-France Hivert, Izzuddin M. Aris, Jaclyn M. Goodrich, Alicia K. Smith, Abigail Gaylord, Rebecca C. Fry, Emily Oken, George O’Connor, Douglas M. Ruden, Leonardo Trasande, Julie B. Herbstman, Carlos A. Camargo, Nicole R. Bush, Anne L. Dunlop, Dana M. Dabelea, Margaret R. Karagas, Carrie V. Breton, Carole Ober, Todd M. Everson, Grier P. Page, Christine Ladd-Acosta, on behalf of program collaborators for Environmental influences on Child Health Outcomes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2023-09-01
Seri Bilgileri:Clinical Epigenetics
Konular:
Epigenetic clock
DNA methylation
Gestational age
Early childhood chronological age
Online Erişim:https://doi.org/10.1186/s13148-023-01552-3
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