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Preparation and evaluation of 2-methoxyestradiol-loaded pH-sensitive liposomes

The development and clinical application of 2-methoxyestradiol (2-ME) as a new type of antitumor drug are limited due to its poor solubility, rapid metabolism in vivo, and large oral dosage. 2-ME-loaded pH-sensitive liposomes (2-ME-PSLs) was prepared containing the lipids, Lipoid E-80 (E-80), choles...

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Bibliografische gegevens
Hoofdauteurs: Suna He, Bowen Wang, Runfang Zhang, Huanhuan Zhou, Qian Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Reeks:Brazilian Journal of Pharmaceutical Sciences
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Online toegang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100544&lng=en&tlng=en
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