Galectin-3 Promotes Müller Glia Clearance Phagocytosis via MERTK and Reduces Harmful Müller Glia Activation in Inherited and Induced Retinal Degeneration

Clearance phagocytosis is a documented function of Müller glia in the retina. However, the molecular mechanisms of Müller glia phagocytosis remain largely undefined. Here, we show that extracellular galectin-3 and protein S promote clearance phagocytosis by immortalized human MIO-M1 Müller cells in...

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Bibliografische Detailangaben

Hauptverfasser:	Deborah S. Lew, Morgan J. McGrath, Silvia C. Finnemann
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-05-01
Schriftenreihe:	Frontiers in Cellular Neuroscience
Schlagworte:	retina retinal degeneration phagocytosis galectin-3 glia Müller cells
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fncel.2022.878260/full
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