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IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential

Abstract The coexistence of two pools of ATP synthase in mitochondria has been largely neglected despite in vitro indications for the existence of reversible active/inactive state transitions in the F1-domain of the enzyme. Herein, using cells and mitochondria from mouse tissues, we demonstrate the...

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Autores principales: Inés Romero-Carramiñana, Pau B. Esparza-Moltó, Sonia Domínguez-Zorita, Cristina Nuevo-Tapioles, José M. Cuezva
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2023-08-01
Colección:Communications Biology
Acceso en línea:https://doi.org/10.1038/s42003-023-05214-1
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