Feasibility and potential diagnostic value of [18F]PI-2620 PET in patients with down syndrome and Alzheimer’s disease: a case series

Purpose of the reportAdults with Down Syndrome (DS) have a substantially increased risk for Alzheimer’s disease (AD) due to the triplicated amyloid-precursor-protein gene on chromosome 21, resulting in amyloid and tau accumulation. However, tau PET assessments are not sufficiently implemented in DS-...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Olivia Wagemann, Matthias Brendel, Nicolai Franzmeier, Georg Nübling, Johannes Gnörich, Mirlind Zaganjori, Catharina Prix, Anna Stockbauer, Elisabeth Wlasich, Sandra V. Loosli, Katja Sandkühler, Lukas Frontzkowski, Günter Höglinger, Johannes Levin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-01-01
coleção:	Frontiers in Neuroscience
Assuntos:	down syndrome Alzheimer tau PET 18F-PI-2620 case series trisomy 21
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1505999/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!