Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via <i>sox9</i> Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

Background: The delivery of therapeutic genes in sites of articular cartilage lesions using non-invasive, scaffold-guided gene therapy procedures is a promising approach to stimulate cartilage repair while protecting the cargos from detrimental immune responses, particularly when targeting chondrore...

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Ngā kaituhi matua:	Jagadeesh K. Venkatesan, Weikun Meng, Ana Rey-Rico, Gertrud Schmitt, Susanne Speicher-Mentges, Céline Falentin-Daudré, Amélie Leroux, Henning Madry, Véronique Migonney, Magali Cucchiarini
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2020-03-01
Rangatū:	Pharmaceutics
Ngā marau:	cartilage repair human bone marrow aspirates raav sox9 pnass-grafted pcl films chondrogenesis
Urunga tuihono:	https://www.mdpi.com/1999-4923/12/3/280
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!