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Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells.

Pulmonary fibrosis is a devastating, incurable disease in which chronic inflammation and dysregulated, excessive wound healing lead to progressive fibrosis, lung dysfunction, and ultimately death. Prior studies have implicated the cytokine IL-17A and Th17 cells in promoting the development of fibros...

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Auteurs principaux: Christine L Vigeland, Samuel L Collins, Yee Chan-Li, Andrew H Hughes, Min-Hee Oh, Jonathan D Powell, Maureen R Horton
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2016-01-01
Collection:PLoS ONE
Accès en ligne:https://doi.org/10.1371/journal.pone.0163288
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