A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests

Background: Antibody tests are essential tools to investigate humoral immunity following SARS-CoV-2 infection or vaccination. While first-generation antibody tests have primarily provided qualitative results, accurate seroprevalence studies and tracking of antibody levels over time require highly sp...

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Principais autores:	Miriam Klausberger, Mark Duerkop, Helmuth Haslacher, Gordana Wozniak-Knopp, Monika Cserjan-Puschmann, Thomas Perkmann, Nico Lingg, Patricia Pereira Aguilar, Elisabeth Laurent, Jelle De Vos, Manuela Hofner, Barbara Holzer, Maria Stadler, Gabriele Manhart, Klemens Vierlinger, Margot Egger, Lisa Milchram, Elisabeth Gludovacz, Nicolas Marx, Christoph Köppl, Christopher Tauer, Jürgen Beck, Daniel Maresch, Clemens Grünwald-Gruber, Florian Strobl, Peter Satzer, Gerhard Stadlmayr, Ulrike Vavra, Jasmin Huber, Markus Wahrmann, Farsad Eskandary, Marie-Kathrin Breyer, Daniela Sieghart, Peter Quehenberger, Gerda Leitner, Robert Strassl, Alexander E. Egger, Christian Irsara, Andrea Griesmacher, Gregor Hoermann, Günter Weiss, Rosa Bellmann-Weiler, Judith Loeffler-Ragg, Nicole Borth, Richard Strasser, Alois Jungbauer, Rainer Hahn, Jürgen Mairhofer, Boris Hartmann, Nikolaus B. Binder, Gerald Striedner, Lukas Mach, Andreas Weinhäusel, Benjamin Dieplinger, Florian Grebien, Wilhelm Gerner, Christoph J. Binder, Reingard Grabherr
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2021-05-01
叢編:	EBioMedicine
主題:	COVID-19 Antibody assay validation Antigen purity Dual-antigen testing SARS-CoV-2 neutralisation Kinetics of primary antibody response
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2352396421001419
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