Influenza A virus NS1 protein represses antiviral immune response by hijacking NF-κB to mediate transcription of type III IFN

BackgroundNon-structural protein 1 (NS1), one of the viral proteins of influenza A viruses (IAVs), plays a crucial role in evading host antiviral immune response. It is known that the IAV NS1 protein regulates the antiviral genes response mainly through several different molecular mechanisms in cyto...

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Principais autores:	Meng-Chang Lee, Cheng-Ping Yu, Xing-Hong Chen, Ming-Tsan Liu, Ji-Rong Yang, An-Yu Chen, Chih-Heng Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-09-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	influenza non-structural protein 1 (NS1) NF-κB IFNL1 chromatin immunoprecipitation and sequencing (ChIP-seq)
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.998584/full
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