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Characterization of the in Vitro Metabolic Profile of Evodiamine in Human Liver Microsomes and Hepatocytes by UHPLC-Q Exactive Mass Spectrometer

Evodiamine is an indoloquinazoline alkaloid isolated from the fruit of Evodia rutaecarpa, which has a wide range of pharmacological effects like anti-tumor and anti-inflammatory effects. This study was intended to investigate the metabolic characteristics of evodiamine in human liver microsomes and...

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Principais autores: Zhaowei Zhang, Tianzi Fang, Hongyun Zhou, Jie Yuan, Qingwang Liu
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-02-01
Serija:Frontiers in Pharmacology
Teme:
Online dostop:http://journal.frontiersin.org/article/10.3389/fphar.2018.00130/full
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