A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR
Self-complementary AAV vectors (scAAV) use a mutant inverted terminal repeat (mITR) for efficient packaging of complementary stranded DNA, enabling rapid transgene expression. However, inefficient resolution at the mITR leads to the packaging of monomeric or subgenomic AAV genomes. These noncanonica...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2024-03-01
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| Seri Bilgileri: | Molecular Therapy: Methods & Clinical Development |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2329050124000226 |
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