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Synthesis and Biological Evaluation of Novel Benodanil-Heterocyclic Carboxamide Hybrids as a Potential Succinate Dehydrogenase Inhibitors

In order to discover new antifungal agents, twenty novel benodanil-heterocyclic carboxamide hybrids were designed, synthesized, and characterized by <sup>1</sup>H NMR and HRMS. In vitro, their antifungal activities against four phytopathogenic fungi were evaluated, as well as some of the target comp...

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Principais autores: Jian Yang, Yongtian Zhao, Jun Wan, Mingfang Jiang, Hong Jin, Ke Tao, Taiping Hou
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-09-01
Serier:Molecules
Fag:
benodanil-heterocyclic carboxamide hybrids
antifungal activity
molecular docking
succinate dehydrogenase inhibitor
Online adgang:https://www.mdpi.com/1420-3049/25/18/4291
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