NSUN2 stimulates tumor progression via enhancing TIAM2 mRNA stability in pancreatic cancer

Abstract NSUN2 is a nuclear RNA methyltransferase which catalyzes 5-methylcytosine (m5C), a posttranscriptional RNA modification. Aberrant m5C modification has been implicated in the development of multiple malignancies. However, its function in pancreatic cancer (PC) needs to be elucidated. Herein,...

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Bibliografische Detailangaben

Hauptverfasser:	Guizhen Zhang, Liwen Liu, Jianhao Li, Yu Chen, Yun Wang, Yize Zhang, Zihui Dong, Wenhua Xue, Ranran Sun, Guangying Cui
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2023-07-01
Schriftenreihe:	Cell Death Discovery
Online-Zugang:	https://doi.org/10.1038/s41420-023-01521-y
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