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Transcriptional signatures of Itk-deficient CD3<sup>+</sup>, CD4<sup>+ </sup>and CD8<sup>+ </sup>T-cells

<p>Abstract</p> <p>Background</p> <p>The Tec-family kinase Itk plays an important role during T-cell activation and function, and controls also conventional versus innate-like T-cell development. We have characterized the transcriptome of Itk-deficient CD3<sup>+ </sup>T-cells, including CD4<sup>+ </...

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Bibliografische Detailangaben
Hauptverfasser: Ellmeier Wilfried, Berglöf Anna, Raberger Julia, Yu Liang, Lindvall Jessica M, Boucheron Nicole, Blomberg K, Smith CI Edvard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2009-05-01
Schriftenreihe:BMC Genomics
Online-Zugang:http://www.biomedcentral.com/1471-2164/10/233
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