In vivo validation of a mechanically adaptive microfluidic intracortical device as a platform for sustained local drug delivery

Introduction: Intracortical microelectrodes (IME) are vital to properly functioning brain-computer interfacing (BCI). However, the recording electrodes have shown a steady decline in performance after implantation, mainly due to chronic inflammation. Compliant materials have been explored to decreas...

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Detalhes bibliográficos

Principais autores:	Youjoung Kim, Lindsey N. Druschel, Natalie Mueller, Danielle Sarno, Kaela Gisser, Allison Hess-Dunning, Jeffrey R. Capadona
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-10-01
coleção:	Frontiers in Biomaterials Science
Assuntos:	intracortical microelectrode mechanically compliant microfluidic in vivo neuroinflammation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbiom.2023.1279367/full
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