A large population sample of African HIV genomes from the 1980s reveals a reduction in subtype D over time associated with propensity for CXCR4 tropism

Abstract We present 109 near full-length HIV genomes amplified from blood serum samples obtained during early 1986 from across Uganda, which to our knowledge is the earliest and largest population sample from the initial phase of the HIV epidemic in Africa. Consensus sequences were made from paired-...

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Detalhes bibliográficos

Principais autores:	Heather E. Grant, Sunando Roy, Rachel Williams, Helena Tutill, Bridget Ferns, Patricia A. Cane, J. Wilson Carswell, Deogratius Ssemwanga, Pontiano Kaleebu, Judith Breuer, Andrew J. Leigh Brown
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-12-01
coleção:	Retrovirology
Assuntos:	HIV Subtype D East Africa Co-receptor Target-capture sequencing Historic samples
Acesso em linha:	https://doi.org/10.1186/s12977-022-00612-5
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