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StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis

How plasma membrane (PM) cholesterol is controlled is poorly understood. Ablation of the gene encoding the ER stress steroidogenic acute regulatory-related lipid transfer domain (StarD)5 leads to a decrease in PM cholesterol content, a decrease in cholesterol efflux, and an increase in intracellular...

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Principais autores: Daniel Rodriguez-Agudo, Leonel Malacrida, Genta Kakiyama, Tavis Sparrer, Carolina Fortes, Michael Maceyka, Mark A. Subler, Jolene J. Windle, Enrico Gratton, William M. Pandak, Gregorio Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019-06-01
coleção:Journal of Lipid Research
Assuntos:
cholesterol trafficking
macrophages
endoplasmic reticulum
Niemann-Pick C
fluorescence
steroidogenic acute regulatory protein-related lipid transfer proteins
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227520322495
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