Diffuse microglial responses and persistent EEG changes correlate with poor neurological outcome in a model of subarachnoid hemorrhage

Abstract The mechanism by which subarachnoid hemorrhage (SAH) leads to chronic neurologic deficits is unclear. One possibility is that blood activates microglia to drive inflammation that leads to synaptic loss and impaired brain function. Using the endovascular perforation model of SAH in rats, we...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Joseph R. Geraghty, Mitchell Butler, Biswajit Maharathi, Alexander J. Tate, Tyler J. Lung, Giri Balasubramanian, Fernando D. Testai, Jeffrey A. Loeb
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2024-06-01
Σειρά:	Scientific Reports
Θέματα:	Subarachnoid hemorrhage Electroencephalography Spectral analysis Inflammation Microglia Fingolimod
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-024-64631-2
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