Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
The nuclear factors κB (NF-κB) is a transcription factor involved in immune functions, inflammation, and cancer. Here, the authors show that the NF-κB factor RELA regulates splicing of target genes by recruiting DDX17 on chromatin upon expression of the viral oncogene Tax.
שמור ב:
| Principais autores: | , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Portfolio
2020-06-01
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| סדרה: | Nature Communications |
| גישה מקוונת: | https://doi.org/10.1038/s41467-020-16853-x |
| תגים: |
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