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Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement

Ca2+/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the actin-crosslinking protein α-actinin-2 underlie long-la...

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Autori principali: Ashton J Curtis, Jian Zhu, Christopher J Penny, Matthew G Gold
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2023-07-01
Serie:eLife
Soggetti:
CaMKII
actinin
long-term potentiation
synapse
dendritic spine
protein kinase
Accesso online:https://elifesciences.org/articles/85008
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