High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.
Ca2+-activated K+ channels have been implicated in cancer cell growth, metastasis, and tumor angiogenesis. Here we hypothesized that high mRNA and protein expression of the intermediate-conductance Ca2+-activated K+ channel, KCa3.1, is a molecular marker of clear cell Renal Cell Carcinoma (ccRCC) an...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2015-01-01
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| Serija: | PLoS ONE |
| Online pristup: | http://europepmc.org/articles/PMC4388734?pdf=render |
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