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RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair

Summary: The Fanconi anemia (FA) pathway is a pivotal genome maintenance network that orchestrates the repair of DNA interstrand crosslinks (ICLs). The tumor suppressors RUNX1 and RUNX3 were shown to regulate the FA pathway independent of their canonical transcription activities, by controlling the...

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Bibliografische Detailangaben
Hauptverfasser: Lavina Sierra Tay, Vaidehi Krishnan, Haresh Sankar, Yu Lin Chong, Linda Shyue Huey Chuang, Tuan Zea Tan, Arun Mouli Kolinjivadi, Dennis Kappei, Yoshiaki Ito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018-08-01
Schriftenreihe:Cell Reports
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2211124718311288
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