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Screening for high coronary plaque volume in primary prevention: integration of multi-omics and coronary calcium scoring into cardiovascular risk assessment

Background: Atherosclerotic plaque volume (PV) predicts future cardiovascular events. As coronary computed tomography angiography (CCTA) is unsuitable for population screening, individuals with high total (T)PV often remain undetected. Objective: To evaluate the relative and incremental contribution...

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Principais autores: Cheng Hwee Soh, Shaun Khanna, Jingqin Wu, Prasanna Venkataraman, Corey Giles, Nitesh Nerlekar, Melinda Carrington, Gerald F Watts, Stephen J Nicholls, Peter Meikle, Thomas H Marwick
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-06-01
Serier:American Journal of Preventive Cardiology
Fag:
Lipidomic risk score
Coronary artery calcium score
Cardiac imaging
Polygenic risk score
Coronary computed tomography angiography
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666667726000553
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