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Histone demethylase KDM6B promotes postnatal oligodendrocyte maturation and cortical myelination

IntroductionPostnatal cortical myelination requires epigenetic activation of oligodendrocyte gene programs, but the role of histone demethylases in vivo remains unclear.MethodsWe conditionally deleted Kdm6b in Emx1+ dorsal telencephalic progenitors and analyzed oligodendrocyte lineage progression, p...

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Principais autores: Ruth Lambries, Zihan Shen, George I. Mias, Jin He
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2026-05-01
丛编:Frontiers in Cellular Neuroscience
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在线阅读:https://www.frontiersin.org/articles/10.3389/fncel.2026.1832157/full
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