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Salmonella Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense.

Regulation of cellular metabolism is now recognized as a crucial mechanism for the activation of innate and adaptive immune cells upon diverse extracellular stimuli. Macrophages, for instance, increase glycolysis upon stimulation with pathogen-associated molecular patterns (PAMPs). Conceivably, path...

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Bibliografiske detaljer
Principais autores: Saray Gutiérrez, Julia Fischer, Raja Ganesan, Nina Judith Hos, Gökhan Cildir, Martina Wolke, Alberto Pessia, Peter Frommolt, Vincenzo Desiderio, Vidya Velagapudi, Nirmal Robinson
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2021-09-01
Serier:PLoS Pathogens
Online adgang:https://doi.org/10.1371/journal.ppat.1009943
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