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Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening

Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten crossbridge detachment, we hypothesized that myocardial relaxation in late systole would be...

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Principais autores: Jane I. Wakefield, Stephen P. Bell, Bradley M. Palmer
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2022-09-01
叢編:Frontiers in Physiology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fphys.2022.980662/full
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